Compile Data Set for Download or QSAR
maximum 50k data
Found 377 of ec50 data for polymerid = 2442,5269,50000644,50000871,50003915
TargetAryl hydrocarbon receptor(Mus musculus (Mouse))
Pfizer

Curated by ChEMBL
LigandPNGBDBM23927(2,3,7,8-Tetrachlorodibenzo-p-dioxin | 2,3,7,8-tetr...)
Affinity DataEC50:  0.0300nMAssay Description:Agonist activity at Ah receptor in genetically engineered mouse cells expressing firefly luciferase gene by CALUX transactivational assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAryl hydrocarbon receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50603549(CHEMBL5203882)
Affinity DataEC50:  0.0300nMAssay Description:Agonist activity at AhR (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAryl hydrocarbon receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50603549(CHEMBL5203882)
Affinity DataEC50:  0.0300nMAssay Description:Agonist activity at AhR in human recombinant HepG2-Lucia AhR cell incubated for 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAryl hydrocarbon receptor(Mus musculus (Mouse))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50602335(CHEMBL5186309)
Affinity DataEC50:  0.0580nMAssay Description:Activation of AhR in mouse NIH3T3 cells assessed as induction of XRE-dependent reporter activity incubated for 4 hrs by Renilla/Firefly based dual-lu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAryl hydrocarbon receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50613370(CHEMBL5285977)
Affinity DataEC50:  0.0971nMAssay Description:Agonist activity at EGFP-tagged human AhR transfected in HEK293 cells assessed as induction of nuclear translocation incubated for 45 mins by fluores...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetAryl hydrocarbon receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50615136(CHEMBL5270440)
Affinity DataEC50:  0.137nMAssay Description:Agonist activity at human AHR in HEK293 cells assessed as nuclear translocation over cytosol incubated for 45 mins by Hoechst staining based assayMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetAryl hydrocarbon receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50615135(CHEMBL5266782)
Affinity DataEC50:  0.161nMAssay Description:Agonist activity at human AHR in HEK293 cells assessed as nuclear translocation over cytosol incubated for 45 mins by Hoechst staining based assayMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetAryl hydrocarbon receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50615134(CHEMBL5265853)
Affinity DataEC50:  0.189nMAssay Description:Agonist activity at human AHR in HEK293 cells assessed as nuclear translocation over cytosol incubated for 45 mins by Hoechst staining based assayMore data for this Ligand-Target Pair
Ligand Info
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TargetAryl hydrocarbon receptor(Homo sapiens (Human))TBA
LigandPNGBDBM7392(2-[(3Z)-2-oxo-2,3-dihydro-1H-indol-3-ylidene]-2,3-...)
Affinity DataEC50:  0.200nMAssay Description:Activation of human AhR expressed in Saccharomyces cerevisiae YCM3 coexpressing ARNT incubated for 18 hrsMore data for this Ligand-Target Pair
TargetAryl hydrocarbon receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50613371(CHEMBL5271031)
Affinity DataEC50:  0.214nMAssay Description:Agonist activity at EGFP-tagged human AhR transfected in HEK293 cells assessed as induction of nuclear translocation incubated for 45 mins by fluores...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetAryl hydrocarbon receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50541261(CHEMBL4646273)
Affinity DataEC50:  0.260nMAssay Description:Agonist activity at AhR in human HepG2 cells assessed as induction of CYP1A1 expression after 24 hrs by ethoxyresorufin-O-deethylase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAryl hydrocarbon receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50603538(CHEMBL5190861)
Affinity DataEC50:  0.270nMAssay Description:Agonist activity at AhR in human recombinant HepG2-Lucia AhR cell incubated for 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAryl hydrocarbon receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50615133(CHEMBL5284079)
Affinity DataEC50:  0.275nMAssay Description:Agonist activity at human AHR in HEK293 cells assessed as nuclear translocation over cytosol incubated for 45 mins by Hoechst staining based assayMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetAryl hydrocarbon receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50615132(CHEMBL5274394)
Affinity DataEC50:  0.297nMAssay Description:Agonist activity at human AHR in HEK293 cells assessed as nuclear translocation over cytosol incubated for 45 mins by Hoechst staining based assayMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetAryl hydrocarbon receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50613366(CHEMBL5280290)
Affinity DataEC50:  0.304nMAssay Description:Agonist activity at EGFP-tagged human AhR transfected in HEK293 cells assessed as induction of nuclear translocation incubated for 45 mins by fluores...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetAryl hydrocarbon receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50603539(CHEMBL5021347)
Affinity DataEC50:  0.340nMAssay Description:Agonist activity at AhR in human recombinant HepG2-Lucia AhR cell incubated for 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAryl hydrocarbon receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50615137(CHEMBL5270280)
Affinity DataEC50:  0.340nMAssay Description:Agonist activity at human AHR in HEK293 cells assessed as nuclear translocation over cytosol incubated for 45 mins by Hoechst staining based assayMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetAryl hydrocarbon receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50613368(CHEMBL5275365)
Affinity DataEC50:  0.389nMAssay Description:Agonist activity at EGFP-tagged human AhR transfected in HEK293 cells assessed as induction of nuclear translocation incubated for 45 mins by fluores...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetAryl hydrocarbon receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50603551(CHEMBL5194336)
Affinity DataEC50:  0.440nMAssay Description:Agonist activity at AhR in human recombinant HepG2-Lucia AhR cell incubated for 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAryl hydrocarbon receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50408372(CHEMBL137408)
Affinity DataEC50:  0.447nMAssay Description:Affinity on cytosolic Aromatic hydrocarbon receptor (Ah)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAryl hydrocarbon receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50613369(CHEMBL5267272)
Affinity DataEC50:  0.468nMAssay Description:Agonist activity at EGFP-tagged human AhR transfected in HEK293 cells assessed as induction of nuclear translocation incubated for 45 mins by fluores...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetAryl hydrocarbon receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50613367(CHEMBL5269910)
Affinity DataEC50:  0.511nMAssay Description:Agonist activity at EGFP-tagged human AhR transfected in HEK293 cells assessed as induction of nuclear translocation incubated for 45 mins by fluores...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetAryl hydrocarbon receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50602335(CHEMBL5186309)
Affinity DataEC50:  0.700nMAssay Description:Activation of AhR in human HaCaT cells assessed as induction of XRE-dependent reporter activity incubated for 4 hrs by Renilla/Firefly based dual-luc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAryl hydrocarbon receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50603554(CHEMBL5181725)
Affinity DataEC50:  0.830nMAssay Description:Agonist activity at AhR in human recombinant HepG2-Lucia AhR cell incubated for 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAryl hydrocarbon receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50408356(CHEMBL136453)
Affinity DataEC50:  1.17nMAssay Description:Affinity on cytosolic Aromatic hydrocarbon receptor (Ah)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAryl hydrocarbon receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50563365(CHEMBL4750416)
Affinity DataEC50:  1.20nMAssay Description:Agonist activity at AhR (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAryl hydrocarbon receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50408320(CHEMBL136430)
Affinity DataEC50:  1.48nMAssay Description:Affinity on cytosolic Aromatic hydrocarbon receptor (Ah)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAryl hydrocarbon receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50408296(CHEMBL341968)
Affinity DataEC50:  1.5nMAssay Description:Affinity on cytosolic Aromatic hydrocarbon receptor (Ah)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAryl hydrocarbon receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50605060(CHEMBL5198290 | US11891386, Compound 004)
Affinity DataEC50:  1.60nMAssay Description:Agonist activity at AhR (unknown origin) transfected in human AZ-AHR reporter cells derived from human HepG2 cells incubated for 4 hrs by luciferase ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAryl hydrocarbon receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50605060(CHEMBL5198290 | US11891386, Compound 004)
Affinity DataEC50:  1.60nMAssay Description:Agonist activity at AhR (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAryl hydrocarbon receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50541262(6-Formylindolo[3,2-B]Carbazole | CHEMBL472031)
Affinity DataEC50:  2nMAssay Description:Agonist activity at AhR in human HepG2 cells assessed as induction of CYP1A1 expression after 24 hrs by ethoxyresorufin-O-deethylase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAryl hydrocarbon receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50563365(CHEMBL4750416)
Affinity DataEC50:  2nMAssay Description:Agonist activity at AHR in human HepG2 cells incubated for 4.5 hrs by Luciferase reporter assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAryl hydrocarbon receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50408359(CHEMBL137055)
Affinity DataEC50:  2nMAssay Description:Affinity on cytosolic Aromatic hydrocarbon receptor (Ah)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAryl hydrocarbon receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50563366(CHEMBL4764225)
Affinity DataEC50:  2nMAssay Description:Agonist activity at AHR in human HepG2 cells incubated for 4.5 hrs by Luciferase reporter assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAryl hydrocarbon receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50563366(CHEMBL4764225)
Affinity DataEC50:  2.5nMAssay Description:Agonist activity at AhR (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAryl hydrocarbon receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50602335(CHEMBL5186309)
Affinity DataEC50:  3.20nMAssay Description:Activation of AhR in human HepG2 cells assessed as induction of XRE-dependent reporter activity incubated for 4 hrs by Renilla/Firefly based dual-luc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAryl hydrocarbon receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50137506((B(a)P) | 3,4-BP | 3,4-Benzopyrene | 3,4-Benzpyren...)
Affinity DataEC50:  5nMAssay Description:Concentration of the compound to bind to human AhR-modied electrodeMore data for this Ligand-Target Pair
TargetAryl hydrocarbon receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50310357(CHEMBL599552 | indigo)
Affinity DataEC50:  5nMAssay Description:Activation of human AhR expressed in Saccharomyces cerevisiae YCM3 coexpressing ARNT incubated for 18 hrsMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAryl hydrocarbon receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50408303(CHEMBL137665)
Affinity DataEC50:  6.61nMAssay Description:Affinity on cytosolic Aromatic hydrocarbon receptor (Ah)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAryl hydrocarbon receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50028963(3-Phenyl-1H-naphtho[2,1-b]pyran-1-one | 3-Phenyl-b...)
Affinity DataEC50:  8.40nMAssay Description:Agonist activity at AhR (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAryl hydrocarbon receptor(Homo sapiens (Human))TBA
LigandPNGBDBM23927(2,3,7,8-Tetrachlorodibenzo-p-dioxin | 2,3,7,8-tetr...)
Affinity DataEC50:  9nMAssay Description:Activation of human AhR expressed in Saccharomyces cerevisiae YCM3 coexpressing ARNT incubated for 18 hrsMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAryl hydrocarbon receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50603555(CHEMBL5199691)
Affinity DataEC50:  9.60nMAssay Description:Agonist activity at AhR in human recombinant HepG2-Lucia AhR cell incubated for 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAryl hydrocarbon receptor(Homo sapiens (Human))TBA
LigandPNGBDBM23927(2,3,7,8-Tetrachlorodibenzo-p-dioxin | 2,3,7,8-tetr...)
Affinity DataEC50:  10nMAssay Description:Affinity on cytosolic Aromatic hydrocarbon receptor (Ah)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAryl hydrocarbon receptor(Mus musculus (Mouse))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50506039(CHEMBL1324296 | US11891386, Compound 002)
Affinity DataEC50:  10nMAssay Description:Agonist activity at AhR in mouse Hepa2Dluc cellsMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAryl hydrocarbon receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50612689(CHEMBL5289699)
Affinity DataEC50:  10nMAssay Description:Agonist activity at AhR (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetAryl hydrocarbon receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50408353(CHEMBL138223)
Affinity DataEC50:  11.5nMAssay Description:Affinity on cytosolic Aromatic hydrocarbon receptor (Ah)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAryl hydrocarbon receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50612690(CHEMBL5267667)
Affinity DataEC50:  12nMAssay Description:Agonist activity at AhR (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetAryl hydrocarbon receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50408369(CHEMBL335558)
Affinity DataEC50:  15.1nMAssay Description:Affinity on cytosolic Aromatic hydrocarbon receptor (Ah)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAryl hydrocarbon receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50408334(CHEMBL135555)
Affinity DataEC50:  15.5nMAssay Description:Affinity on cytosolic Aromatic hydrocarbon receptor (Ah)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAryl hydrocarbon receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50408300(CHEMBL422101)
Affinity DataEC50:  17.0nMAssay Description:Affinity on cytosolic Aromatic hydrocarbon receptor (Ah)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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